Journal of Pathology and Translational Medicine

Baek hui Kim

5 Articles

Primary Malignant Melanoma Arising in an Ovarian Mature Cystic Teratoma: A Case Report and Literature Review.: Sangho Lee, Ji Hoon Kim, Gyu Rak Chon, Aeree Kim, Baek Hui Kim; Korean J Pathol. 2011;45(6):659-664.; DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.6.659

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Ovarian primary malignant melanoma is very uncommon with only 44 reported cases in the literature. A 71-year-old woman with an ovarian mass and multiple nodules in the liver presented to our hospital. She was treated with bilateral salpingo-oophorectomy, and malignant melanoma was found in the mature cystic teratoma of the ovary. Malignant melanoma cells were also found in the ascitic fluid. She died 5 months later. Here we report a very uncommon case of malignant melanoma arising in an ovarian mature cystic teratoma with a review of the literature.

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Malignant Transformation of an Ovarian Mature Cystic Teratoma to a Malignant Melanoma
Rita Rathore, Sana Ahuja, Nuneno Nakhro, Pallavi Punhani, Sufian Zaheer
Indian Journal of Surgical Oncology.2024;[Epub] CrossRef
Malignant melanoma arising in mature teratoma with pugnacious spread: A case report
Sumedha Gupta, Shalu Solanki, Saritha Shamsunder, Sana Ahuja, Vinayak Varma
Indian Journal of Obstetrics and Gynecology Research.2024; 11(1): 119. CrossRef
Therapeutic Management of Rare Primary Ovarian Neoplasms: Carcinosarcoma, Leiomyosarcoma, Melanoma and Carcinoid
Mateusz Kozłowski, Katarzyna Nowak, Agnieszka Kordek, Aneta Cymbaluk-Płoska
International Journal of Environmental Research and Public Health.2021; 18(15): 7819. CrossRef
Primary form of malignant melanoma in an ovarian mature cystic teratoma: case report and literature review
Fatemeh Samiee-rad, Amir Abdollah Zangivand, Kamran Soleimanitadi
Comparative Clinical Pathology.2017; 26(4): 989. CrossRef
Malignant melanoma arising in a mature teratoma: A case report with review of the recent literature
Lorna A. Brudie, Faizan Khan, Michael J. Radi, Melissa M. Yates, Sarfraz Ahmad
Gynecologic Oncology Reports.2016; 16: 47. CrossRef
Metastasizing Primary Malignant Melanoma of the Ovary: A Diagnostic Enigma
Narendra Hulikal, Manilal Banoth, Revanth Gangasani, Praveen C. Suresh, Radhika Kottu, Asha Thota
Journal of Gynecologic Surgery.2015; 31(3): 166. CrossRef

Reappraisal of 'The Korean Journal of Pathology, 2010; 44: 111-6' by Youngjoon Ryu et al. and Comments on 'The Korean Journal of Pathology, 2010; 44: 343-5' by Kyu Won Jung and Soong Deok Lee.: Youngjoon Ryu, Bongkyung Shin, Baek Hui Kim, Aeree Kim, Hankyeom Kim; Korean J Pathol. 2010;44(5):453-455.; DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.5.453

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Abstract PDF: No abstract available.

Legal and Ethical Consideration in the Use of Human Biological Material.: Youngjoon Ryu, Bongkyung Shin, Baek Hui Kim, Aeree Kim, Hankyeom Kim; Korean J Pathol. 2010;44(2):111-116.; DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.2.111

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Abstract PDF

Traditionally, pathologists have used human biological material primarily for diagnostic purposes. More recently, advances in biomedical technology and changes in the research environment have placed new demands on pathologists and their handling of human materials. Moreover, these technological advances have required pathologists to be not only experts in diagnosis, but also managers of biobanks storing human biological material. Consequently, pathologists might now be confronted with unanticipated legal and ethical questions. We investigated seven examples of South Korean legislation concerning human biological material, including "The Bioethics and Safety Act" (2005), and we considered possible conflicts of interest between donors and researchers. We also reviewed international bioethical guidelines and legal precedents from several countries with special regard to pathologic glass slides, paraffin blocks, remaining specimens and other guidelines. We conclude that a better understanding of the legal and ethical questions concerning human biological material leads pathologists to safer and more conscientious management of these samples.

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Proposal for the development of a human biological material management system for research hospitals
Young-Joon Ryu, Hankyeom Kim, Sejin Jang
Journal of the Korean Medical Association.2012; 55(3): 292. CrossRef

Malignant Mesothelioma in Body Fluids: with Special Reference to Differential Diagnosis from Metastatic Adenocarcinoma.: Jin Ho Paik, Jin Haeng Chung, Baek Hui Kim, Gheeyoung Choe; Korean J Pathol. 2009;43(5):458-466.; DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.5.458

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Abstract PDF: BACKGROUND
Malignant mesothelioma (MM) is a rare malignant neoplasm occurring in pleura, pericardium, and peritoneum. The differential diagnosis between MM and metastatic adenocarcinoma (MA) causes diagnostic, staging, and therapeutic dilemmas. Herein, we investigated characteristic cytologic features of MM.
METHODS
Cytologic specimens of MM (n=10), MA (n=25), and reactive mesothelial hyperplasia (n=10) were retrieved and reviewed from archival materials in the Department of Pathology, Seoul National University Bundang Hospital from May 2003 to July 2008.
RESULTS
MM showed tumor cell clusters and singly scattered malignant tumor cells forming single cell populations with sparse reactive benign mesothelial cells. In contrast, MA showed distinct two cell populations of tumor cell clusters and scattered reactive mesothelial cells. Furthermore, MM frequently exhibited a characteristic long chain-like arrangement (hand-in-hand appearance) and intercellular windows, which were rarely evident in MA. Variable nuclear size, relatively consistent nuclear-cytoplasmic ratio, bior multi-nucleation, and lacy cytoplasmic borders were also frequently observed in MM.
CONCLUSIONS
Differential diagnosis of MM from MA in body fluids is possible based on meticulous examination of certain cytologic parameters, which could have significant implications in staging and treatment.

Epstein-Barr virus-associated Inflammatory Pseudotumor-like Follicular Dendritic Cell Tumor in the Spleen of a Patient with Diffuse Large B Cell Lymphoma: A Case Report and Review of the Literature.: Sun Och Yoon, Hyoungsuk Ko, Baek hui Kim, Ghee Young Kwon, Yoon Kyung Jeon, Chul Woo Kim; Korean J Pathol. 2007;41(3):198-202.

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Abstract PDF: We report a case of an Epstein-Barr virus (EBV)-associated inflammatory pseudotumor-like follicular dendritic cell tumor (IPT-like FDC tumor). The tumor occurred in the spleen of a 64-year-old woman with a history of a diffuse large B-cell lymphoma (DLBCL) of neck nodes that presented four years ago. The splenectomy specimen revealed a 5 cm-sized, tan-colored and well-circumscribed mass. Histologically, spindle or ovoid cells with large vesicular nuclei were admixed with abundant inflammatory cells. Immunohistochemically, spindle cells were positive for FDC marker CD35, but negative for CD20, CD30 and ALK. EBV was detected almost exclusively in spindle cells by EBER in situ hybridization. IPT-like FDC tumors are rare, and are recognized as a distinctive clinicopathologic variant of FDC tumors. Among only 18 similar cases reported in the English language literature, the present case is the first case of a patient with a history of DLBCL.

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